CARDIOLOGIE Pubmed artikelen Intrinsic versus laser-induced fluorescence spectroscopy for coronary atherosclerosis: a generational comparison model for testing diagnostic accuracy. van de Poll SW, Angheloiu GO, Georgakoudi I, Motz JT, Haka AS, Podrez E, Fitzmaurice M, Dasari RR, Feld MS, Kramer JR. Appl Spectrosc. 2012 Dec;66(12):1403-10 doi: 10.1366/11-06566. PMID: 23231902. Abstract Laser-induced fluorescence (LIF) and intrinsic fluorescence spectroscopy (IFS) have been used experimentally for diagnosing coronary atherosclerosis. In this study, we demonstrated the diagnostic superiority of IFS at 342-nm excitation (IFS(342)) versus LIF (LIF(342)) and described a protocol for head-to-head comparison of old (LIF) versus new (IFS) generations of similar diagnostic methods, labeled as “generational comparison model”. IFS(342) and LIF(342) were modeled with basis spectra of media, fibrous caps, and superficial foam cells and of their correspondent chemicals (elastin, collagen, and lipoproteins). The average accuracy and receiver operating characteristic area under the curve of IFS(342) in single-, double-, and triple-parameter diagnostic algorithm iterations, geared toward identifying 84 atherosclerotic specimens from a group of 117 coronary segments, was 90% ± 1% and 0.87 ± 0.025, superior to LIF(342) (84% ± 3% and 0.84 ± 0.016; P = 0.0002 and 0.02, respectively) in a generational comparison model. A somnolent man found in the park – rhythm puzzle. Pieters C, van de Poll SW. Neth Heart J. 2012 Sep;20(9):382-3. doi: 10.1007/s12471-012-0316-4. PMID: 22890620. Geen abstract. PMC: 3430765. Free PMC article. Onion-like masses in the left ventricle. Baars JE, Edward Visser W, Hoedemaeker R, Pieters C, van Miltenburg AJ. Eur Heart J Cardiovasc Imaging. 2012 Oct 2. [Epub ahead of print] PMID: 23034993. Geen abstract Overige artikelen A somnolent man found in the park – answer. Pieters C, van de Poll SW. Neth Heart J. 2012 Sep;20(9):379. doi: 10.1007/s12471-012-0315-5. 11 Cursief: werkzaam in het Sint Franciscus Gasthuis WETENSCHAPPELIJK jaarverslag 2012 Pagina 10
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