GYNAECOLOGIE Pubmed artikelen Laparoscopic sacrocolpopexy with bone anchor fixatio: short-term anatomic and functional results. Withagen MI, Vierhout ME, Mannaerts GHH, Van der Weiden RMF. Int Urogynecol J 2012; 23: 481-6. PMID: 22086264. INTRODUCTION AND HYPOTHESIS: The aim of this study was to evaluate short-term anatomic and functional outcomes and safety of laparoscopic sacrocolpopexy with bone anchor fixation.METHODS: A prospective cohort study of women undergoing laparoscopic sacrocolpopexy between 2004 and 2009. Anatomic outcome was assessed using the pelvic organ prolapse quantification score (POP-Q). Functional outcomes were assessed using the Urogenital Distress Inventory, Defecatory Distress Inventory, and the Incontinence Impact Questionnaire preoperatively and at 6 months postoperatively. The Wilcoxon signed rank test was used to test differences between related samples. RESULTS: Forty-nine women underwent laparoscopic sacrocolpopexy. The objective success rate in the apical compartment was 98%, subjective success rate was 79%. One mesh exposure (2%) was found. One conversion was necessary due to injury to the ileum. CONCLUSIONS: Laparoscopic sacrocolpopexy with bone anchor fixation is a safe and efficacious treatment for apical compartment prolapse. It provides excellent apical support and good functional outcome 6 months postoperatively. Successful myomectomy of a bleeding myoma in a twin pregnancy. Doerga – Bachasingh SR, Karsdorp VHM, Yo G, Van der Weiden RMF, Van Hooff MHA. JRSM Short Rep 2012;3: 13. PMID: 22393474. Geen abstract. DOI 10.1258 / shorts.2011.011087. PMCID: 3291420. Free article. Succesfull treatment of pituitary tumour apoplexy with bromocryptine in pregnancy. Jansen NM, Dreyer K, Van der Weiden RMF. JRSM Short Rep 2012; 3: 43. PMID: 22768377. Geen abstract. DOI 10.1258 / shorts.2012.011144. PMCID: 338661. Free article. Prospective evaluation of molecular screening for Lynch syndrome in patients with endometrial cancer = 70 years. Leenen CH, Van Lier MG, Van Doorn HC, Van Leerdam ME, Kooi SG, de Waard J, Hoedemaeker RF, Van den Ouweland AM, Hulspas SM, Dubbink HJ, Kuipers EJ, Wagner A, Dinjens WN, Steyerberg EW. Gynecol Oncol. 2012;125:414-20. Epub 2012 Feb 1. PMID: 22306203. DOI: 10.1016/j.ygyno.2012.01.049. Lynch syndrome (LS) is a hereditary syndrome that predisposes to multiple malignancies including endometrial cancer (EC). We aimed to evaluate a diagnostic strategy for LS based on routine analysis of microsatellite instability (MSI) and immunohistochemical (IHC) staining for mismatch repair (MMR) proteins in tumour tissue of all newly diagnosed EC patients =70 years. 27 WETENSCHAPPELIJK jaarverslag 2012 Pagina 26

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